Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 8, Issue 6, Pages 1406-1414Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b924619c
Keywords
-
Categories
Funding
- Zylum-Beteiligungsgesellschaft mbH Co.
Ask authors/readers for more resources
Arene diazonium tetrafluoroborates can be synthesized from aromatic acetamides via a sequence of deacetylation, diazotation and precipitation, induced by anion exchange. The reaction is conducted as a convenient one-flask transformation with consecutive addition of the appropriate reagents. Exchange of solvents or removal of byproducts prior to isolation of the product is not required. The arene diazonium salts are isolated from the reaction mixture by simple filtration. Two complementary protocols are presented, and the utility of the reaction is exemplified for a synthesis of the diarylheptanoid natural product de-O-methyl centrolobine.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available