Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 8, Issue 9, Pages 1993-2002Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b925075a
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Funding
- EPSRC
- Royal Society
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Peptide and protein thioesters are playing an increasingly prominent role in the chemical toolbox for protein assembly and modification through Native Chemical Ligation (NCL). In this Emerging Area we highlight recent developments in a somewhat surprising route to thioesters: selective disruption of amides, the more stable carboxylic acid derivatives.
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