Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 8, Issue 3, Pages 533-535Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b919526b
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Funding
- BBSRC [BB/D002826/1, BB/G023581/2] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BB/G023581/2, BB/D002826/1] Funding Source: Medline
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A short chemoenzymatic synthesis of beta-aryl-gamma-aminobutyric acids has been developed, based on a highly enantioselective biocatalytic reduction of beta-aryl-beta-cyano-alpha, beta-unsaturated carboxylic acids.
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