4.6 Article

Impregnated copper on magnetite: an efficient and green catalyst for the multicomponent preparation of propargylamines under solvent free conditions

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 8, Issue 1, Pages 43-46

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b917923b

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Funding

  1. Spanish Ministerio de Ciencia y Tecnologia [2010 CSD2007-00006, CTQ2007-65218/BQU]
  2. Consolider Ingenio

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Impregnated copper on magnetite is a versatile, inexpensive and simple catalyst for the selective multicomponent reaction of terminal alkynes, aldehydes and secondary amines to give the corresponding propargylamines with excellent yields. The catalyst can be easily recovered and reused by using a simple magnet. The process could be repeated up to ten times without losing its activity.

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