Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 8, Issue 20, Pages 4533-4535Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0ob00353k
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Streptomyces sp. GF3587 and 3546 were found to be iminereducing strains with high R- and S-selectivity by screening using 2-methyl-1-pyrroline (2-MPN). Their whole-cell catalysts produced 91 mM R-2-methylpyrrolidine (R-2-MP) with 99.2% e.e. and 27.5 mM S-2-MP (92.3% e.e.) from 2-MPN at 91-92% conversion in the presence of glucose, respectively.
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