4.6 Article

A highly selective and sensitive fluorescent turn-on sensor for Hg2+ and its application in live cell imaging

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 7, Issue 12, Pages 2554-2558

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b902912e

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Funding

  1. National Basic Research Program of China [2006CB806104, 2007CB925103]
  2. NSFC [20875043, 20775017]
  3. Shanghai Leading Academic Discipline Project [B108]

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A boron-dipyrromethene (BODIPY) derivative containing a tridentate diaza-oxa ligand (8H-BDP) was synthesized as a fluorescent turn-on chemosensor for Hg2+ with high sensitivity (detection limit <= 2 ppb), a rapid response time (<= 5 seconds) and specific selectivity over other cations under physiological conditions and in live cells according to the confocal fluorescence microscopy experiment.

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