4.6 Article

Remarkable increase in basicity associated with supramolecular gelation

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 7, Issue 15, Pages 3091-3094

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b904523f

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Funding

  1. Ministerio de Educacion y Ciencia [CTQ2006-14984]
  2. Universitat Jaume I - Bancaixa

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L-Proline derivatives which are able to form supramolecular gels show an amazing basicity increase in the aggregated (gel) state as compared to solution. As a result they behave as enantioselective catalysts for the aldol reaction in solution but produce a base-catalyzed aldol racemisation in the gel state.

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