Alkynylation of aryl halides with perfluoro-tagged palladium nanoparticles immobilized on silica gel under aerobic, copper- and phosphine-free conditions in water

The utilization of perfluoro-tagged palladium nanoparticles immobilized on fluorous silica gel through fluorous-fluorous interactions (Pd-np-A/FSG) or linked to silica gel by covalent bonds (Pd-np-B) in the alkynylation of terminal alkynes with aryl halides under aerobic, copper-and phosphine-free conditions in water, and their recovery and re-utilization, is described.