Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 7, Issue 11, Pages 2259-2264Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b901198f
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Funding
- NIH NIGMS [R01-GM076320]
- Bristol Myers Squibb
- Eli Lilly
- Roche
- Beckman Foundation
- Packard Foundation
- Sloan Foundation
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM076320] Funding Source: NIH RePORTER
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A new cyanosulfur-ylide based linker makes possible the synthesis of C-terminal peptide alpha-ketoacids by solid phase synthesis. The preparation of the requisite linker and its application to a variety of C-terminal peptide alpha-ketoacids with unprotected side chains is reported.
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