Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 7, Issue 8, Pages 1627-1632Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b821134p
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An efficient metal-free Sonogashira coupling protocol catalysed by DABCO is reported, where very good conversions and selectivities to the cross-coupling product were obtained under mild reaction conditions. The reported solvent-, phosphane- and metal-free protocol, that uses a cheap base as catalyst, considerably improves the green credentials of the reaction.
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