4.6 Article

A hydrophilic three side-chained triazatruxene as a new strong and selective G-quadruplex ligand

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 7, Issue 12, Pages 2513-2516

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b904723a

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Funding

  1. MIUR (Italian Ministry of University)
  2. Sapienza Universita di Roma

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A new hydrosoluble triazatruxene derivative (AZATRUX) is reported to selectively bind to G-quadruplex DNA, as derived by ESI-MS measurements and competition experiments.

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