Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 7, Issue 4, Pages 665-670Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b816847d
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- EC
- BBSRC
- Wellcome Trust
- Royal Society
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We have previously shown that dipeptides can be synthesised in high yields from amino acids using protease catalysis in aqueous media, if the amino component is immobilised on porous PEGA resin (a copolymer of polyethylene glycol and polyacrylamide). Here we explore the scope of this methodology for using protected and glycosylated amino acids as well as the synthesis of longer peptides on resin and show that such a method can also be applied on non-porous surfaces, in particular on gold.
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