4.6 Article

Synthesis of a photo-caged aminooxy alkane thiol

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 7, Issue 23, Pages 4954-4959

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b904195h

Keywords

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Funding

  1. National Science Foundation Career Award [CHE-0645793]
  2. NSF IGERT: Materials Creation Training Program [(MCTP)-DGE-0654431]
  3. California Nanosystems Institute
  4. NIH
  5. Jonsson Comprehensive Cancer Center (JCCC)
  6. Alfred P. Sloan Foundation
  7. NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [T32GM067555] Funding Source: NIH RePORTER

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A photo-caged aminooxy alkane thiol synthesized in 7 steps and 15% overall yield was used to form a self-assembled monolayer (SAM). Photo-deprotection on the surface was confirmed by FT-IR spectroscopy and contact angle goniometry. Conjugation of a small molecule ketone, ethyl levulinate, further confirmed the presence of aminooxy groups on the surface.

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