4.6 Article

Synthesis and stereochemical determination of batzelladine C methyl ester

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 7, Issue 23, Pages 5001-5009

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b914744f

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Funding

  1. EPSRC
  2. AstraZeneca

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Batzelladine C (3) is a tricyclic guanidine alkaloid of unknown stereochemistry at one centre as well as unknown absolute stereochemistry. The two possible diastereoisomers of the methyl ester corresponding to this compound have been synthesised, permitting the relative and absolute stereochemistry of this compound to be assigned.

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