4.6 Article

Peptide thioester synthesis through N -> S acyl-transfer: application to the synthesis of a beta-defensin

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 7, Issue 23, Pages 4918-4923

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b913886b

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Funding

  1. EPSRC
  2. MRC
  3. Royal Society
  4. Medical Research Council [MC_U127527201] Funding Source: researchfish
  5. MRC [MC_U127527201] Funding Source: UKRI

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Peptide thioesters readily prepared through N -> S acyl transfer of a specific C-terminal motif provide access to biologically active mini-proteins using native chemical ligation.

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