Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 7, Issue 22, Pages 4782-4788Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b915274a
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- Region Bretagne
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A series of thieno[2,3-d]- and thieno[3,2-d]pyrimidines have been easily synthesized using as key step a deproto-cadmiation-trapping sequence. Some of the compounds thus synthesized were screened for anticancer (cytotoxic) activities, and (S)-2-(6-iodo-2-phenylthieno[2,3-d]pyrimidin-4-ylamino)-3-phenylpropanoic acid proved to have a significant activity towards liver, human breast and cervix carcinoma cell lines.
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