4.6 Article

A modular flow reactor for performing Curtius rearrangements as a continuous flow process

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 6, Issue 9, Pages 1577-1586

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b801631n

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The use of a mesofluidic flow reactor is described for performing Curtius rearrangement reactions of carboxylic acids in the presence of diphenylphosphoryl azide and trapping of the intermediate isocyanates with various nucleophiles.

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