Journal
ORAL DISEASES
Volume 20, Issue 3, Pages e1-e6Publisher
WILEY
DOI: 10.1111/odi.12192
Keywords
randomized control trials; burning mouth syndrome; BMS; placebo; treatment; oral dysesthesia
Categories
Ask authors/readers for more resources
Placebo controls play a critical role in the evaluation of any pharmacotherapy. This review surveys the placebo arm in 12 randomized controlled trials (RCTs) investigating burning mouth syndrome (BMS) and documents a positive placebo response in 6 of them. On average, treatment with placebos produced a response that was 72% as large as the response to active drugs. The lack of homogeneity in the use of placebos adds to the difficulty in comparing results and aggregating data. Future RCTs investigating BMS would benefit from larger sample sizes, adequate follow-up periods, and use of a standard placebo.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available