Journal
OPTICS LETTERS
Volume 37, Issue 5, Pages 800-802Publisher
OPTICAL SOC AMER
DOI: 10.1364/OL.37.000800
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Funding
- National Institutes of Health [1RC1CA145105]
- Duke University
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We demonstrate a cross-phase modulation measurement technique based on the sensitive detection of modulation transfer in a pump-probe setup. By modulating the amplitude of the pump beam and spectrally analyzing the probe beam, we achieve a rapid, background-free measurement of nonlinear phase modulation using power levels acceptable in biological imaging. This measurement technique would allow the extension of widely employed phase microscopy methods to the nonlinear regime, providing intrinsic and universal nonlinear contrast for biological imaging. (C) 2012 Optical Society of America
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