Journal
OPTICS LETTERS
Volume 36, Issue 2, Pages 139-141Publisher
OPTICAL SOC AMER
DOI: 10.1364/OL.36.000139
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Funding
- National Institutes of Health (NIH) [R01 EB000712, R01 EB008085, R01 CA134539, U54 CA136398, R01 EB010049, 5P60 DK02057933]
- Microphotoacoustics, Inc.
- Endra, Inc.
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We developed a photoacoustic imaging system that has real-time imaging capability with optical resolution. The imaging system is capable of scanning at 20 Hz over a 9 mm range and up to 40 Hz over a 1 mm scanning range. A focused laser beam provides a lateral resolution of 3.4 mu m as measured in an optically nonscattering medium. Flows of micrometer-sized carbon particles or whole blood in a silicone tube and individual red blood cells (RBCs) in mouse ear capillaries were also imaged in real time, demonstrating the capability to image highly dynamic processes in vivo at a micrometer-scale resolution. (C) 2011 Optical Society of America
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