Journal
OPTICS LETTERS
Volume 35, Issue 8, Pages 1245-1247Publisher
OPTICAL SOC AMER
DOI: 10.1364/OL.35.001245
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- Forschungskredit of the University of Zurich
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A major limitation of any type of microscope is the penetration depth in turbid tissue. Here, we demonstrate a fundamentally novel kind of fluorescence microscope that images through optically thick turbid layers. The microscope uses scattered light, rather than light propagating along a straight path, for imaging with subwavelength resolution. Our method uses constructive interference to focus scattered laser light through the turbid layer. Microscopic fluorescent structures behind the layer were imaged by raster scanning the focus. (C) 2010 Optical Society of America
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