4.6 Article

In vivo photoacoustic imaging of transverse blood flow by using Doppler broadening of bandwidth

Journal

OPTICS LETTERS
Volume 35, Issue 9, Pages 1419-1421

Publisher

OPTICAL SOC AMER
DOI: 10.1364/OL.35.001419

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Funding

  1. National Institutes of Health (NIH) [R01 EB000712, R01 NS46214, R01 EB008085, R01 CA113453901, U54 CA136398, 5P60 DK02057933]
  2. Microphotoacoustics, Inc.
  3. Endra, Inc.
  4. NATIONAL CANCER INSTITUTE [R01CA134539, U54CA136398] Funding Source: NIH RePORTER
  5. NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [R01EB000712, R01EB008085] Funding Source: NIH RePORTER
  6. NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE [R01NS046214] Funding Source: NIH RePORTER

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A method is proposed to measure transverse blood flow by using photoacoustic Doppler broadening of bandwidth. By measuring bovine blood flowing through a plastic tube, the linear dependence of the broadening on the flow speed was validated. The blood flow of the microvasculature in a mouse ear and a chicken embryo (stage 16) was also studied. (C) 2010 Optical Society of America

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