Journal
OPTICS EXPRESS
Volume 21, Issue 23, Pages 28729-28742Publisher
OPTICAL SOC AMER
DOI: 10.1364/OE.21.028729
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Funding
- DOE [DE-FG02-11ER16210]
- Human Frontier Science Program
- AMOS program within the Chemical Sciences, Geosciences, and Biosciences Division of the Office of Basic Energy Sciences, Office of Science, U.S. DOE
- Max Planck Society
- Hamburg Ministry of Science and Research and Joachim Herz Stiftung as part of the Hamburg Initiative for Excellence in Research (LEXI)
- Hamburg School for Structure and Dynamics in Infection
- Swedish Research Council
- European Research Council
- Knut och Alice Wallenbergs Stiftelse
- US Department of Energy by Lawrence Livermore National Laboratory [DE-AC52-07NA27344]
- UCOP Lab Fee Program [118036]
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Single shot diffraction imaging experiments via X-ray free-electron lasers can generate as many as hundreds of thousands of diffraction patterns of scattering objects. Recovering the real space contrast of a scattering object from these patterns currently requires a reconstruction process with user guidance in a number of steps, introducing severe bottlenecks in data processing. We present a series of measures that replace user guidance with algorithms that reconstruct contrasts in an unsupervised fashion. We demonstrate the feasibility of automating the reconstruction process by generating hundreds of contrasts obtained from soot particle diffraction experiments. (C) 2013 Optical Society of America
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