Journal
OPTICS EXPRESS
Volume 19, Issue 9, Pages 8179-8186Publisher
OPTICAL SOC AMER
DOI: 10.1364/OE.19.008179
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Funding
- Deutsche Forschungsgemeinschaft (DFG)
- State of Baden-Wurttemberg through the DFG-Center for Functional Nanostructures (CFN) [A5.5]
- Concept for the Future of the KIT within the framework of the German Excellence Initiative
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Laser light excitation of fluorescent markers offers highly sensitive and specific analysis for bio-medical or chemical analysis. To profit from these advantages for applications in the field or at the point-of-care, a plastic lab-on-a-chip with integrated organic semiconductor lasers is presented here. First order distributed feedback lasers based on the organic semiconductor tris(8-hydroxyquinoline) aluminum (Alq(3)) doped with the laser dye 4-dicyanomethylene-2-methyl-6-(p-dimethylaminostyril)-4H-pyrane (DCM), deep ultraviolet induced waveguides, and a nanostructured microfluidic channel are integrated into a poly(methyl methacrylate) (PMMA) substrate. A simple and parallel fabrication process is used comprising thermal imprint, DUV exposure, evaporation of the laser material, and sealing by thermal bonding. The excitation of two fluorescent marker model systems including labeled antibodies with light emitted by integrated lasers is demonstrated. (C) 2011 Optical Society of America
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