Journal
OPTICS EXPRESS
Volume 19, Issue 5, Pages 4157-4169Publisher
OPTICAL SOC AMER
DOI: 10.1364/OE.19.004157
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- Wellcome Trust
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We present a new, robust and automated method for registering sequences of images acquired from scanning ophthalmoscopes. The method uses a multi-scale B-spline representation of the deformation field to map images to each other and an hierarchical optimization method. We applied the method to video sequences acquired from different parts of the retina. In all cases, the registration was successful, even in the presence of large distortions from microsaccades, and the resulting deformation fields describe the fixational motion of the eye. The registration reveals examples of dynamic photoreceptor behaviour in the sequences. (C) 2011 Optical Society of America
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