Journal
OPTICS EXPRESS
Volume 18, Issue 23, Pages 23544-23553Publisher
Optica Publishing Group
DOI: 10.1364/OE.18.023544
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Funding
- Universidad Autonoma de Madrid
- Comunidad Autonoma de Madrid [CCG087-UAM/MAT-4434, S2009/MAT-1756]
- Spanish Ministerio de Educacion y Ciencia [MAT 2007-64686]
- Banco Santander-CEAL-UAM project
- Natural Sciences and Engineering Research Council (NSERC) of Canada
- Gouvernement du Quebec, Ministere du Developpement economique, de l'Innovation et de l'Exportation
- Spanish Ministry of Education [AP2006-02795]
- Spanish Minsterio de Educacion at Concordia University [PR2009-0040]
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In this paper, we demonstrate for the first time that the new class of fluoride-based inorganic upconverting nanoparticles, NaYF4:Er3+, Yb3+, are the most efficient multiphoton excited fluorescent nanoparticles developed to date. The near-infrared-to-visible conversion efficiency of the aforementioned nanoparticles surpasses that of CdSe quantum dots and gold nanorods, which are the commercially available inorganic fluorescent nanoprobes presently used for multiphoton fluorescence bioimaging. The results presented here open new perspectives for the implementation of fluorescence tomography by multiphoton fluorescence imaging. (C) 2010 Optical Society of America
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