Journal
OPTICS EXPRESS
Volume 17, Issue 17, Pages 14780-14790Publisher
OPTICAL SOC AMER
DOI: 10.1364/OE.17.014780
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Funding
- NIH Biomedical Technology Resource [P41-RR01192]
- Beckman Foundation
- Military Photomedicine Program
- AFOSR [FA9550-08-1-0384]
- Hewitt Foundation for Medical Research
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We present a wide-field method for obtaining three-dimensional images of turbid media. By projecting patterns of light of varying spatial frequencies on a sample, we reconstruct quantitative, depth resolved images of absorption contrast. Images are reconstructed using a fast analytic inversion formula and a novel correction to the diffusion approximation for increased accuracy near boundaries. The method provides more accurate quantification of optical absorption and higher resolution than standard diffuse reflectance measurements. (C) 2009 Optical Society of America
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