4.6 Article

Single-pass volumetric bidirectional blood flow imaging spectral domain optical coherence tomography using a modified Hilbert transform

Journal

OPTICS EXPRESS
Volume 16, Issue 16, Pages 12350-12361

Publisher

OPTICAL SOC AMER
DOI: 10.1364/OE.16.012350

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Funding

  1. NEI NIH HHS [R21 EY017393] Funding Source: Medline
  2. NIBIB NIH HHS [R21 EB006338] Funding Source: Medline

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We demonstrate in vivo volumetric bidirectional blood flow imaging in animal models using single-pass flow imaging spectral domain optical coherence tomography. This technique uses a modified Hilbert transform algorithm to separate moving and non-moving scatterers within a depth. The resulting reconstructed image maps the components of moving scatterers flowing into and out of the imaging axis onto opposite image half-planes, enabling volumetric bidirectional flow mapping without manual segmentation. (C) 2008 Optical Society of America.

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