4.6 Article

Specific detection of proteins using photonic crystal waveguides

Journal

OPTICS EXPRESS
Volume 16, Issue 20, Pages 15949-15957

Publisher

OPTICAL SOC AMER
DOI: 10.1364/OE.16.015949

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Funding

  1. U. S. Air Force Office of Scientific Research
  2. Natural Sciences and Engineering Research Council of Canada (NSERC)
  3. National Research Council of Canada National Institute of Nanotechnology (NRC-NINT)

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Specific detection of proteins is demonstrated using planar photonic crystal waveguides. Using immobilized biotin as probe, streptavidin was captured, causing the waveguide mode cut-off to red-shift. The device was shown to detect a 2.5 nm streptavidin film with a 0.86 nm cut-off red-shift. An improved photonic crystal waveguide sensor design is also described and shown to have a 40% improved bulk refractive index response. (C) 2008 Optical Society of America

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