Journal
OPTICAL MATERIALS
Volume 36, Issue 11, Pages 1792-1797Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.optmat.2014.04.018
Keywords
LiGa5O8:Cr3+; Long afterglow; Near infrared luminescence; In vivo imaging
Categories
Funding
- National Natural Science Funds of China [51102201]
- Xiamen Funds for Distinguished Young Scientists
- Xiamen University of Technology
- National Key Technology Support Program [2012BAC25B04]
- Science and Technology Project in Xiamen [3502Z20132012]
Ask authors/readers for more resources
The Cr3+-doped LiGa5O8 nanoparticles (LGNPs) with long-persistent near-infrared phosphorescence were obtained through a sal-gel approach followed by heat treatment at 800 degrees C in air. The obtained results reveal that the nanoparticles with an average diameter of 100 nm are well defined and have pure structure of LiGa5O8. After illumination for 3 min using a 254 nm UV lamp, the LGNPs exhibit strong near-infrared peak at ca. 720 nm belonging to tissue transparency window which can last for more than 1 h. Via surface modified with PEG-5000-OCH3, the LGNPs-PEG-OCH3 exhibit excellent biocompatibility and low toxicity. Under in vitro pre-excitation using a 254 nm UV lamp for 3 min, the in vivo distribution of the LGNPs-PEG-OCH3 in the abdomen can be detected in real time for more than 1 h. All the results indicate that the LGNPs-PEG-OCH3 can be used as potential nanoprobes to realize in vivo, real time and long time imaging with high sensitivity. (C) 2014 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available