Journal
OPTICAL MATERIALS
Volume 35, Issue 11, Pages 1976-1980Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.optmat.2012.10.049
Keywords
Samarium-doped glass; Fluorophosphate glass; Fluoroaluminate glass; Valency conversion; Dosimetry; Microbeam Radiation Therapy (MRT)
Categories
Funding
- NSERC
- NRC
- Canadian Institutes of Health Research
- Province of Saskatchewan
- Western Economic Diversification Canada
- University of Saskatchewan
- New Zealand Ministry for Science and Innovation
- Teledyne-DALSA through an NSERC Strategic Grant
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Microbeam Radiation Therapy (MRT) is a promising cancer treatment technique. During the treatment, a micro-planar lattice of narrow X-ray beams called a microbeam (each narrow X-ray beam is typically 20-100 mu m wide separated by 100-400 mu m) delivers a very large dose (>1000 Gy) onto a tumor. Sm3+-doped glasses that involve the reduction of the Sm-valency (Sm3+ -> Sm2+) upon X-ray irradiation are one of the potential dosimetric detectors for this particular application. With this class of detectors, we use the extent of valency reduction as a measure of the delivered X-ray dose, and the response read out using a confocal microscopic technique via the Sm2+/Sm3+ photoluminescence. This method enables us to measure the dose distribution of the microbeam. In this paper, we show that both Sm3+-doped fluorophosphate and fluoroaluminate glasses exhibit a dynamic range for the conversion response from 1 to over 1000 Gy, which satisfies the dose range for MRT applications. The dynamic range depends on the concentration of Sm3+ dopants as well as the detector glass composition. Moreover, X-ray induced absorbance, photobleaching and thermally-stimulated luminescence (TL) measurements suggest that the hole trapping process during X-ray irradiation is a dominant factor for the valency conversion, and the accommodation of precursor POHCs in fluorophosphate glasses gives rise to an acceleration of the conversion process. (C) 2012 Elsevier B.V. All rights reserved.
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