Journal
TETRAHEDRON LETTERS
Volume 56, Issue 7, Pages 903-906Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2014.12.142
Keywords
Multicomponent reaction; Metal-free; Propargylamines; Petasis-borono Mannich reaction; Decarboxylative coupling
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Funding
- National Key Technology RD Program [2011BAE06B05-4]
- Shanghai Key Laboratory of Catalysis Technology for Polyolefins [LCTP-201301]
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A metal-free multicomponent coupling reaction of aliphatic amines, formaldehyde, organoboronic acids, and propiolic acids has been reported for the synthesis of diverse propargylamines. This transformation involves a MCR2 of PBM and decarboxylative three-component coupling reactions. (C) 2015 Elsevier Ltd. All rights reserved.
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