4.4 Article

Direct amination of 2-(1-tosylalkyl)phenols with aqueous ammonia: a metal-free synthesis of primary amines

Journal

TETRAHEDRON LETTERS
Volume 56, Issue 9, Pages 1135-1137

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2015.01.078

Keywords

Amination; 2-(1-Tosylalkyl)phenols; Aqueous ammonia; Metal-free; Primary amines

Funding

  1. National Natural Science Foundation of China [21125208, 20921092]
  2. National Basic Research Program of China [2010CB833300]

Ask authors/readers for more resources

A metal-free and concise method for the selective synthesis of primary amines directly from 2-(1-tosylalkyl)phenols with aqueous ammonia under mild conditions has been developed. In addition, primary amine could be conveniently converted to benzoxazinone in good yield. (C) 2015 Elsevier Ltd. All rights reserved.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.4
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available