4.4 Article

Total synthesis of natural and pharmaceutical products powered by organocatalytic reactions

Journal

TETRAHEDRON LETTERS
Volume 56, Issue 17, Pages 2133-2140

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2015.03.046

Keywords

Total synthesis; Organocatalytic reactions; Natural products

Funding

  1. National Natural Science Foundation of China [21172246, 21290180, 21472210]
  2. Youth Innovation Promotion Association, Chinese Academy of Sciences

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Organocatalysis has emerged as the third pillar of modern asymmetric catalysis in the past two decades. Applying organocatalytic reactions in total synthesis is currently a highly dynamic research area. This Digest focuses on selected recent examples of total synthesis of natural and pharmaceutical products enabled by organocatalytic reactions, highlighting the importance of organocatalytic reactions in fostering structures of biological importance. (C) 2015 Published by Elsevier Ltd.

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