Journal
TETRAHEDRON LETTERS
Volume 56, Issue 23, Pages 3208-3211Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2014.12.104
Keywords
Munchnone; 1,3-Dipolar cycloaddition; Atorvastatin; Pyrrole; Mesoionic
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Atorvastatin was prepared in seven steps from commercially available 4-fluorophenylacetic acid. The key 1,3-dipolar cycloaddition was conducted regioselectively using a complex munchnone which was prepared in five steps on decagram scale. (C) 2015 Elsevier Ltd. All rights reserved.
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