Journal
TETRAHEDRON LETTERS
Volume 56, Issue 23, Pages 3075-3081Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2014.11.046
Keywords
Nitrogen heterocycles; Biosynthesis; Amino acid morphing; Enzymatic transformations
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Nitrogen-containing heterocycles are central to the chemical reactions that occur in all organisms. The metabolic transformation of amino acids into five, six, and seven-member heterocycles reveals the chemical logic and enzymatic machinery for shunting primary metabolites into bioactive heterocyclic nitrogen scaffolds. (C) 2014 Elsevier Ltd. All rights reserved.
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