Journal
TETRAHEDRON LETTERS
Volume 56, Issue 13, Pages 1703-1705Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2015.02.055
Keywords
Trifluoromethylation; Indole; Copper-catalyzed; Togni's reagent
Categories
Ask authors/readers for more resources
Modern drug discovery has created an increasing demand for new methods of trifluoromethylation. Herein a novel method for the synthesis of trifluoromethylated fused tricyclic indoles by copper(I) iodide as catalyst has been successfully developed under mild conditions. The corresponding trifluoromethyl indoles were obtained with good to excellent yields (62-89%) and the reaction applies to a different range of functional groups. (C) 2015 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available