4.4 Article

Oxidative conversion of δ-sultones to γ-lactones

Journal

TETRAHEDRON LETTERS
Volume 56, Issue 17, Pages 2269-2271

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2015.03.038

Keywords

Sultone; Lactone; C-H insertion

Funding

  1. National Institutes of Health [GM085645]
  2. National Foundation [CHE-0216038]

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delta-Sultones, prepared by C-H insertion, can be oxidatively converted to gamma-lactones by treatment with t-BuOK/r-BuOOH. An intermediate in the synthesis of (-)-eburnamonin was prepared using this approach. (C) 2015 Elsevier Ltd. All rights reserved.

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