4.4 Article

N-(Pyridin-2-yl)benzamide: efficient ligand for the nickel catalyzed Chan-Lam cross-coupling reaction

Journal

TETRAHEDRON LETTERS
Volume 56, Issue 48, Pages 6685-6688

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2015.10.047

Keywords

Chan-Lam; C-N coupling; Ni catalyst; TMG; Benzamide

Funding

  1. University Grants Commission (UGC), New Delhi

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An efficient protocol for the Chan Lam cross-coupling reactions of arylboronic acids with aryl or alkyl amines has been developed by employing simple N-(pyridin-2-yl)benzamide ligand with Ni (OAc)(2)center dot 4H(2)O in the presence of TMG base. The reaction proceeded well with high yields by employing various N-nucleophiles at low catalytic loadings. (C) 2015 Elsevier Ltd. All rights reserved.

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