4.4 Article

A general and inexpensive protocol for the Cu-catalyzed C-S cross-coupling reaction between aryl halides and thiols

Journal

TETRAHEDRON LETTERS
Volume 56, Issue 47, Pages 6560-6564

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2015.10.014

Keywords

Catalysis; Copper; C-S coupling; DABCO; Thioetherification

Funding

  1. Kerala State Council for Science, Technology, and Environment (KSCSTE), Trivandrum [341/2013/KSCSTE]
  2. Council of Scientific and Industrial Research (CSIR, India)
  3. University Grants Commission (UGC, India)

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A cost effective and easily available CuI/DABCO catalytic system has been developed for C-S cross-coupling reaction. This method is extremely useful for the thioetherification of aryl and heteroaryl halides providing excellent yields and good chemoselectivity. (C) 2015 Elsevier Ltd. All rights reserved.

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