Journal
TETRAHEDRON LETTERS
Volume 56, Issue 1, Pages 32-52Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2014.11.061
Keywords
Propargylic amides; Transition-metal-catalyzed cyclization; Electrophilic cyclization
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Funding
- National Natural Science Foundation of China [21172218]
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Cyclization reactions of propargylic amides, due to their rapid assembly of structural complexity and good functional group compatibility, have gained considerable attention in recent years. These transformations have been successfully achieved with transition metals, halogen sources, Bronsted acids, and strong bases. Generally, the cyclizations proceed through a 5-exo-dig or 6-endo-dig fashion to furnish heterocycles. (C) 2014 Published by Elsevier Ltd.
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