4.4 Article

The preparation of 2-substituted-3-diazoquinolin-4-ones

Journal

TETRAHEDRON LETTERS
Volume 56, Issue 1, Pages 53-55

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2014.09.061

Keywords

Heterocycles; Quinolones; Diazo compound; Aminoquinoline; Substitutions

Funding

  1. Ministry of Education, Youth and Sport of the Czech Republic [IGA 453103071/31 PrF_2013_025, SPP 813103131/12, CZ.1.07/2.3.00/20.0009]

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A series of 2-substituted-3-diazoquinolin-4-ones is prepared by the reaction of 2-substituted-3-amino-4-chloroquinolines with sodium nitrite in sulfuric acid. Some of the obtained products are then utilised in triazole formation, reduction and a Wolff rearrangement/Friedel-Crafts ketene capture. (C) 2014 Published by Elsevier Ltd.

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