4.4 Article

The insertion of arynes into the O-H bond of aliphatic carboxylic acids

Journal

TETRAHEDRON LETTERS
Volume 56, Issue 40, Pages 5470-5473

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2015.08.019

Keywords

Arylation; Insertion; Aliphatic carboxylic acid; Aryne

Funding

  1. National Natural Science Foundation of China [21242002]
  2. 100 Young Talents Programme of Guangdong University of Technology [220413506]

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The insertion of arynes into the O-H bond of aliphatic carboxylic acids promoted by sodium carboxylates is described. The reactions led to the formation of aryl carboxylates in good yields with good chemoselectivities under mild conditions. (C) 2015 Elsevier Ltd. All rights reserved.

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