Journal
TETRAHEDRON LETTERS
Volume 56, Issue 3, Pages 558-561Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2014.11.117
Keywords
Organocatalyst; Diaminomethylenemalononitrile; Aldol; Ketone; Solvent-free
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Funding
- Grants-in-Aid for Scientific Research [24790015] Funding Source: KAKEN
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Pyrrolidine-diaminomethylenemalononitrile (pyrrolidine-DMM) organocatalyst has been an efficient reaction medium to promote asymmetric direct aldol reactions to afford the corresponding addition products in high yields with up to 99% ee under solvent-free conditions. (C) 2014 Elsevier Ltd. All rights reserved.
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