Journal
TETRAHEDRON LETTERS
Volume 56, Issue 6, Pages 842-846Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2014.12.122
Keywords
Enaminoketones; 2,6-Diarylnicotinaldehydes; Microwave irradiation; Conventional heating; First examples
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Funding
- CSIR
- UGC, New Delhi
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Enaminoketones undergo unexpected self condensation in acetic acid to produce a wide range of 2,3,6-trisubstituted pyridine derivatives in excellent yields in the presence of NH4OAc. This is the first Letter on the synthesis of 2,6-diarylnicotinaldehydes. The reaction was studied under microwave irradiation and conventional heating. However, mixed condensations were observed when two different enaminones are combined. (C) 2015 Published by Elsevier Ltd.
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