Journal
TETRAHEDRON
Volume 71, Issue 40, Pages 7706-7716Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2015.07.057
Keywords
Diverse synthesis; Domino reactions; Tunable reactions; Lewis base catalysts; Allenoate chemistry
Categories
Funding
- National Natural Science Foundation of China [21403154]
- Natural Foundation of Tianjin [13JCYBJC38700]
- Tianjin Municipal Education Commission [20120502]
- Key Laboratory of Chemical Synthesis and Pollution Control of Sichuan Province [CSPC2014-4-1]
- 131 talents program of Tianjin
Ask authors/readers for more resources
We first reported an example of diverse synthesis of pyrano[2,3-b]indol and dihydropyrano[2,3-b]indol from the same starting materials. In these domino reactions, we can control the reaction conditions to give three new products: pyrano[2,3-b]indol, dihydropyrano[2,3-b]indol with E or Z exocyclic double bond. Using DABCO as catalyst in THF, dihydropyrano[2,3-b]indol with E exocyclic double bond and pyrano[2,3-b]indol were obtained at room temperature and 65 degrees C, respectively. In contrast, when DMAP was selected as catalyst, dihydropyrano[2,3-b]indol with Z exocyclic double bond was formed in toluene at 80 degrees C. (C) 2015 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available