4.4 Article

Heterocycles from wine: synthesis and biological evaluation of salidrosides

Journal

TETRAHEDRON
Volume 71, Issue 20, Pages 3115-3119

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2014.08.065

Keywords

Wine polyphenols; Tannins; Salidroside; Galloyl-substituted salidrosides; Antimicrobial activity

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Wine is composed of a variety of tannins, of which a sub-class includes salidrosides, which are largely uninvestigated compounds. The first syntheses of galloylated salidrosides are reported in 7 steps from commercially available starting materials through a platform approach. The antimicrobial activity of the salidrosides against Escherichia coli strains is described. (C) 2014 Elsevier Ltd. All rights reserved.

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