Journal
ONCOLOGIST
Volume 13, Issue 7, Pages 769-778Publisher
WILEY
DOI: 10.1634/theoncologist.2007-0251
Keywords
solid organ transplantation; Kaposi sarcoma; lymphoproliferative disorders; etiology; treatment
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With improving survival following solid organ transplantation, clinicians must be aware of post-transplant complications. One increasingly frequent complication is the development of malignancy after transplantation. The most common malignancies encountered in the post-solid organ transplant setting are nonmelanoma skin cancers, post-transplant lymphoproliferative disorders, and Kaposi's sarcoma (KS). The pathogenesis of these tumors is likely related to the immunosuppressive drugs used post-transplantation and subsequent viral infection. Treatment involves modification of the immunosuppressive drug regimen, resection of localized disease, and chemotherapy. We present the second reported case of a patient with lung transplantation who developed KS in the lung graft.
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