Journal
TETRAHEDRON
Volume 71, Issue 29, Pages 4842-4845Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2015.05.025
Keywords
Probe; Hydrogen peroxide; Near-infrared; ROS
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Funding
- National Natural Science Foundation of China [81172936, 91213303]
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A new near-infrared and colorimetric fluorescent molecular probe was developed for rapid detection of H2O2. The near-infrared fluorescence OFF ON switch is triggered by transformation of phenylboronic acid unit to phenol in the presence of H2O2. No quinone methides are released in this process, which is preferable for in vivo studies. In addition, probe 1 at low concentration exhibits high quality optical imaging during a short period in in vitro cell study. (C) 2015 Elsevier Ltd. All rights reserved.
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