4.8 Article

VEGF drives cancer-initiating stem cells through VEGFR-2/Stat3 signaling to upregulate Myc and Sox2

Related references

Note: Only part of the references are listed.
Article Medicine, Research & Experimental

GLI1 regulates a novel neuropilin-2/61 integrin based autocrine pathway that contributes to breast cancer initiation

Hira Lal Goel et al.

EMBO MOLECULAR MEDICINE (2013)

Article Medicine, Research & Experimental

Tumor VEGF:VEGFR2 autocrine feed-forward loop triggers angiogenesis in lung cancer

Sampurna Chatterjee et al.

JOURNAL OF CLINICAL INVESTIGATION (2013)

Review Oncology

VEGF targets the tumour cell

Hira Lal Goel et al.

NATURE REVIEWS CANCER (2013)

Article Immunology

Autocrine VEGF-VEGFR2-Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth

Petra Hamerlik et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2012)

News Item Pharmacology & Pharmacy

Comprehensive care and care at the center of the new recommendation HAS

Elisa Derrien

ACTUALITES PHARMACEUTIQUES (2012)

Editorial Material Medicine, General & Internal

Fighting Fire with Fire: Rekindling the Bevacizumab Debate

Alberto J. Montero et al.

NEW ENGLAND JOURNAL OF MEDICINE (2012)

Article Biochemistry & Molecular Biology

Sox2 expression in breast tumours and activation in breast cancer stem cells

O. Leis et al.

ONCOGENE (2012)

Article Multidisciplinary Sciences

Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia

Sarah J. Conley et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Multidisciplinary Sciences

A SUMOylation-Dependent Transcriptional Subprogram Is Required for Myc-Driven Tumorigenesis

Jessica D. Kessler et al.

SCIENCE (2012)

Article Oncology

Bevacizumab in the Treatment of Metastatic Breast Cancer: Friend or Foe?

Alberto J. Montero et al.

CURRENT ONCOLOGY REPORTS (2012)

Article Multidisciplinary Sciences

Interactions between cancer stem cells and their niche govern metastatic colonization

Ilaria Malanchi et al.

NATURE (2012)

Article Cardiac & Cardiovascular Systems

VEGF/SDF-1 promotes cardiac stem cell mobilization and myocardial repair in the infarcted heart

Jun-Ming Tang et al.

CARDIOVASCULAR RESEARCH (2011)

Review Cell & Tissue Engineering

Eyes Wide Open: A Critical Review of Sphere-Formation as an Assay for Stem Cells

Erika Pastrana et al.

CELL STEM CELL (2011)

Article Cell Biology

Vascular endothelial growth factor receptor 3 directly regulates murine neurogenesis

Charles-Felix Calvo et al.

GENES & DEVELOPMENT (2011)

Article Medicine, Research & Experimental

The JAK2/STAT3 signaling pathway is required for growth of CD44+CD24- stem cell-like breast cancer cells in human tumors

Lauren L. C. Marotta et al.

JOURNAL OF CLINICAL INVESTIGATION (2011)

Review Oncology

Targeting cancer stem cells by inhibiting Wnt, notch, and Hedgehog pathways

Naoko Takebe et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2011)

Article Hematology

VEGF Induces Differentiation of Functional Endothelium From Human Embryonic Stem Cells Implications for Tissue Engineering

Marilyn B. Nourse et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2010)

Article Biochemistry & Molecular Biology

Autocrine VEGF Signaling Synergizes with EGFR in Tumor Cells to Promote Epithelial Cancer Development

Beate M. Lichtenberger et al.

Editorial Material Cell Biology

THE CHANGING FACES OF CANCER CELLS

Xin-Hua Feng

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)

Review Oncology

Targeting the tumour vasculature: insights from physiological angiogenesis

Alicia S. Chung et al.

NATURE REVIEWS CANCER (2010)

Editorial Material Oncology

Inflammation and Cancer: IL-6 and STAT3 Complete the Link

Jacqueline Bromberg et al.

CANCER CELL (2009)

Article Biotechnology & Applied Microbiology

Effect of VEGF on the Regenerative Capacity of Muscle Stem Cells in Dystrophic Skeletal Muscle

Bridget M. Deasy et al.

MOLECULAR THERAPY (2009)

Review Oncology

Anticancer strategies involving the vasculature

Victoria L. Heath et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2009)

Review Oncology

An overview of small-molecule inhibitors of VEGFR signaling

S. Percy Ivy et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2009)

Article Multidisciplinary Sciences

Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features

Chad J. Creighton et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Cell & Tissue Engineering

Angiogenic Capacity of Human Adipose-Derived Stromal Cells During Adipogenic Differentiation: An In Vitro Study

Femke Verseijden et al.

TISSUE ENGINEERING PART A (2009)

Review Biochemistry & Molecular Biology

Vascular endothelial growth factor-dependent and -independent regulation of angiogenesis

Masabumi Shibuya

BMB REPORTS (2008)

Article Multidisciplinary Sciences

Stat3 and c-Myc Genome-Wide Promoter Occupancy in Embryonic Stem Cells

Benjamin L. Kidder et al.

PLOS ONE (2008)

Article Cell & Tissue Engineering

Regulation of Sox2 by STAT3 initiates commitment to the neural precursor cell fate

Kara M. Foshay et al.

STEM CELLS AND DEVELOPMENT (2008)

Review Oncology

MYC - TIMELINE Reflecting on 25 years with MYC

Natalie Meyer et al.

NATURE REVIEWS CANCER (2008)

Review Oncology

VEGF-targeted therapy: mechanisms of anti-tumour activity

Lee M. Ellis et al.

NATURE REVIEWS CANCER (2008)

Article Cell & Tissue Engineering

ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome

Christophe Ginestier et al.

CELL STEM CELL (2007)

Article Oncology

Making a tumour's bed: glioblastoma stem cells and the vascular niche

Richard J. Gilbertson et al.

NATURE REVIEWS CANCER (2007)

Article Oncology

A perivascular niche for brain tumor stem cells

Christopher Calabrese et al.

CANCER CELL (2007)

Review Medicine, Research & Experimental

Angiogenesis modulates adipogenesis and obesity

Yihai Cao

JOURNAL OF CLINICAL INVESTIGATION (2007)

Article Multidisciplinary Sciences

Angiogenesis-independent tumor growth mediated by stem-like cancer cells

Per O. Sakariassen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Review Cell Biology

VEGF receptor signalling - in control of vascular function

AK Olsson et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)

Review Oncology

Normal stem cells and cancer stem cells: The niche matters

Linheng Li et al.

CANCER RESEARCH (2006)

Article Multidisciplinary Sciences

Genes that mediate breast cancer metastasis to lung

AJ Minn et al.

NATURE (2005)

Article Biochemistry & Molecular Biology

A novel role for vascular endothelial growth factor as an autocrine survival factor for embryonic stem cells during hypoxia

K Brusselmans et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Review Oncology

Mammary stem cells, self-renewal pathways, and carcinogenesis

SL Liu et al.

BREAST CANCER RESEARCH (2005)

Article Multidisciplinary Sciences

Prospective identification of tumorigenic breast cancer cells

M Al-Hajj et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)